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What is oxandrolone? oxandrolone is a man-made steroid, similar to the naturally occurring steroid testosterone. Oxandrolone is an "anabolic" steroid that promotes the growth of muscle tissue. Oxandrolone is used to help you regain weight lost after surgery, severe trauma, or chronic infections. Oxandrolone is no exception. Ln the above-cited study on hiv+ males, twelve weeks of 20 mg or 40 mg per day caused an approximate 45% reduction in serum testosterone ievels. The group taking 80 mg noticed a 66% decrease in testosterone. Anavar 10mg (oxandrolone) dosage. Men: 30 mg to 80 mg per day · women: 5 mg to 15 mg per day. We’ve seen dosages as high as 100 mg per day for men and 20 mg per day for women, but it’s not very common. Oxandrolone is a steroid. This medicine is used to help people gain weight. It is also used to treat bone pain in patients with osteoporosis. 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